
Globally, psychological well being problems and substance use problems (SUDs) contribute considerably to the general burden of illness, with many of those circumstances rising throughout adolescence. As soon as dismissed as mere “rising pains”, these circumstances considerably have an effect on high quality of life and social functioning. It has beforehand been estimated that every yr, round 25% of adolescents expertise a psychological well being dysfunction, rising to 33% over their lifetime (Kessler et al., 2007).
As emphasised by Beth Cumber in her latest Psychological Elf weblog, early intervention is important for bettering psychological well being outcomes on this inhabitants. Equally, in his 2022 weblog, Alejandro Arguelles Bullon highlighted the significance of age-stratified analyses to grasp danger patterns throughout adolescence, because it permits researchers to establish specific factors of vulnerability and potential intervention.
In opposition to this backdrop, Kieling et al. (2024) used the most recent 2019 International Burden of Illness (GBD) information to analyse the worldwide prevalence and well being burden of psychological well being problems and substance use problems (SUDs) amongst completely different age teams throughout childhood and adolescence. Their findings reveal essential traits of psychological well being problems throughout adolescence and provide clear instructions for early intervention, offering very important proof for policymakers and healthcare employees.

The significance of early intervention and prevention in baby and adolescent psychological well being is more and more recognised, with age-stratified analyses permitting researchers to establish traits and factors of intervention.
Strategies
The International Burden of Illnesses, Accidents, and Threat Components Examine (GBD) is a large inhabitants examine that began within the early Nineteen Nineties to quantify ranges and traits in well being throughout the globe.
The present examine by Kieling et al. (2024) analysed the worldwide prevalence and well being burden of psychological problems and SUDs amongst 2,516 million people aged 5–24 years utilizing information from the 2019 GBD examine. Knowledge sources included nationwide well being surveys, hospital data, and worldwide stories. Knowledge had been stratified by distinct age teams (5–9, 10–14, 15–19, and 20–24 years) and gender. Findings had been cross-validated with unbiased datasets to make sure reliability. The Explanation for Dying Ensemble Mannequin (CODEm) was performed to regulate for comorbidities. Well being burden was quantified utilizing Years Lived with Incapacity (YLDs).
Outcomes
In 2019, 11.63% of people aged 5-24 years (roughly 293 million) had a minimum of one psychological well being dysfunction, whereas 1.22% (roughly 31 million) had a SUD (see Desk 1 under). Nervousness problems had been essentially the most prevalent (3.35%; 84 million), and schizophrenia was the least frequent (0.08%; 2 million). Boys confirmed increased charges of neurodevelopmental problems reminiscent of autism and attention-deficit hyperactivity dysfunction (ADHD), whereas ladies had higher prevalence of hysteria, temper, and consuming problems.
Concerning well being burden, psychological well being problems accounted for 20.27% (31.14 million of 153.59 million) of YLDs in youngsters and youths aged 5-24 years, the very best amongst all well being circumstances. SUDs contributed to 4.30 million YLDs. YLDs elevated dramatically with age, with nearly 5-fold will increase within the variety of YLDs within the age 20-24 years, in comparison with the age 5-9 years. Essentially the most stark enhance was for depressive problems, the place the variety of YLDs rose 35-fold from 5-9 years to 20-24 years.
From a broader life course perspective throughout all ages, 24.85% (31.14 million of 125.29 million) of whole YLDs related to psychological problems happen within the age 5 to 24 years, highlighting their vital burden in comparison with different well being circumstances like cardiovascular ailments (5.30%) and diabetes (3.15%).
Desk 1. Prevalence of a minimum of one psychological well being dysfunction throughout age teams
Age group (years) | Prevalence (% [95% CI]) |
5 to 9 | 6.81% [5.60 to 8.03] |
10 to 14 | 12.42% [10.57 to 14.45] |
15 to 19 | 13.96% [12.37 to 15.78] |
20 to 24 | 13.63% [11.91 to 15.53] |
5 to 24 (all) | 11.63% (weighted imply) |

In 2019, roughly 293 million youngsters and adolescents aged 5-24 years skilled a minimum of one psychological well being dysfunction, with anxiousness problems being essentially the most prevalent.
Conclusions
This examine by Kieling and colleagues (2024) highlights the worldwide prevalence of psychological well being problems in youngsters and adolescents aged 5–24 years, with anxiousness problems and temper problems being the first contributors. Psychological well being problems account for 20.27% of non-fatal well being burdens from all GBD problems in people aged 5-24 years. Furthermore, over the life course, 24.85% of all well being burden attributable to psychological well being problems was present in individuals aged 5-24 years, reversing the standard patterns noticed in different well being circumstances reminiscent of cardiovascular ailments and diabetes.
These psychological well being circumstances have a profound affect on schooling, social participation, and financial alternatives, with the burden notably excessive in low- and middle-income nations (LMICs). As such, this examine emphasises the urgent want for an elevated concentrate on early screening and intervention efforts, age-specific useful resource allocation, and prioritising adolescent psychological well being as a world well being concern. Policymakers are urged to deal with these challenges by evidence-based interventions and sustainable psychological well being insurance policies.

Between the ages of 5-9 and 20-24 years, the prevalence of getting a minimum of one psychological well being dysfunction doubles, highlighting the significance of early intervention and prevention efforts throughout this developmental interval.
Strengths and limitations
Strengths
- The examine adopts an age-stratified evaluation, providing detailed insights into psychological well being dysfunction prevalence and well being burden throughout distinct age teams throughout childhood and adolescence. It additionally offers evidence-based suggestions, emphasizing the significance of age-specific information for useful resource allocation and focused interventions.
- The examine used the information from GBD, which is collected from throughout 204 nations and areas and contains a variety of knowledge sources, reminiscent of systematic critiques, authorities stories, and worldwide databases. This worldwide protection permits for cross-regional comparisons, supporting extra inclusive and culturally delicate well being insurance policies.
- The examine employs a comorbidity adjustment mechanism to deal with the overlap of a number of problems inside people, lowering bias and guaranteeing unbiased and correct estimates of every dysfunction’s burden throughout age, gender, and area.
Limitations
- Knowledge from LMICs are restricted in high quality, with over 170 million youngsters and youths dwelling in data-scarce areas. Moreover, high-risk teams reminiscent of LGBTQIA+ youth and Indigenous adolescents are underrepresented. Such regional variations in information assortment and reporting additional have an effect on cross-region comparability.
- Knowledge sources differ by age group, with parental stories used for youthful youngsters and self-reports for adolescents, inflicting inconsistencies in information interpretation. Exclusion of subclinical displays additionally doubtlessly underestimates the true burden of psychological well being points.
- The examine depends on 2019 cross-sectional information, limiting insights into longitudinal impacts of those psychological well being circumstances. Moreover, it doesn’t account for the affect of the COVID-19 pandemic, which had a widespread unfavorable affect on the psychological well being of kids and adolescents.
- Variations in diagnostic requirements, cultural perceptions, and reporting practices throughout areas might introduce observer bias, affecting the accuracy and comparability of prevalence estimates. Though the information had been adjusted to account for identified biases, there stays some uncertainty about their accuracy.

Whereas the usage of a world dataset permits for cross-regional comparisons, there may be restricted information from low- and middle-income nations, alongside underrepresentation from high-risk teams.
Implications for apply
This examine highlights the pressing want for early intervention and age-specific psychological well being methods at a world scale. Insurance policies should prioritise enough funding, stigma discount, and accessible healthcare for kids and adolescents, particularly in LMICs.
Throughout my internship at a psychiatric hospital in China, I noticed that folks usually sought skilled assist solely when their youngsters’s educational efficiency had declined, and after a essential incident, reminiscent of self-harm or suicide. Earlier indicators of psychological misery had been missed or not recognised. This lack of understanding might result in delayed intervention, which might additional negatively affect educational efficiency, emotional stability, interpersonal relationships, and private improvement, all of which I witnessed throughout my intervention.
Moreover, psychological well being stigma stays a significant barrier to well timed entry to skilled assist (Golberstein et al., 2008). Addressing psychological well being in childhood and adolescence requires not solely scientific interventions however cultural shifts—fostering consciousness, acceptance, and proactive assist techniques all through society. This necessitates elevated communication between completely different techniques, reminiscent of faculties and healthcare companies.
Throughout my internship, I seen that faculties usually lacked the diagnostic instruments and coaching essential to establish and deal with psychological well being points at an early stage, whereas healthcare techniques incessantly operated in isolation, with restricted communication and collaboration with faculties and households. This brought about many missed alternatives for early intervention.

With a purpose to enhance well timed entry to psychological well being assist, we have to enhance consciousness of the early indicators of psychological misery in youngsters and adolescents.
Assertion of pursuits
None.
Hyperlinks
Main paper
Kieling, C., Buchweitz, C., Caye, A., Silvani, J., Ameis, S. H., Brunoni, A. R., … & Szatmari, P. (2024). Worldwide prevalence and incapacity from psychological problems throughout childhood and adolescence: proof from the worldwide burden of illness examine. JAMA Psychiatry, 81(4), 347-356.
Different references
Bullon, A. A. (2022). International burden of illness from psychological problems stays excessive. The Psychological Elf.
Cumber, B. (2024). Prevention is the place it’s at for kids and younger individuals’s psychological well being. The Psychological Elf.
Golberstein, E., Eisenberg, D., & Gollust, S. E. (2008). Perceived stigma and psychological well being care looking for. Psychiatric Companies, 59(4), 392-399.
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, Ok. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV problems within the Nationwide Comorbidity Survey Replication. Archives of Basic Psychiatry, 62(6), 593-602.
Photograph credit

Globally, psychological well being problems and substance use problems (SUDs) contribute considerably to the general burden of illness, with many of those circumstances rising throughout adolescence. As soon as dismissed as mere “rising pains”, these circumstances considerably have an effect on high quality of life and social functioning. It has beforehand been estimated that every yr, round 25% of adolescents expertise a psychological well being dysfunction, rising to 33% over their lifetime (Kessler et al., 2007).
As emphasised by Beth Cumber in her latest Psychological Elf weblog, early intervention is important for bettering psychological well being outcomes on this inhabitants. Equally, in his 2022 weblog, Alejandro Arguelles Bullon highlighted the significance of age-stratified analyses to grasp danger patterns throughout adolescence, because it permits researchers to establish specific factors of vulnerability and potential intervention.
In opposition to this backdrop, Kieling et al. (2024) used the most recent 2019 International Burden of Illness (GBD) information to analyse the worldwide prevalence and well being burden of psychological well being problems and substance use problems (SUDs) amongst completely different age teams throughout childhood and adolescence. Their findings reveal essential traits of psychological well being problems throughout adolescence and provide clear instructions for early intervention, offering very important proof for policymakers and healthcare employees.

The significance of early intervention and prevention in baby and adolescent psychological well being is more and more recognised, with age-stratified analyses permitting researchers to establish traits and factors of intervention.
Strategies
The International Burden of Illnesses, Accidents, and Threat Components Examine (GBD) is a large inhabitants examine that began within the early Nineteen Nineties to quantify ranges and traits in well being throughout the globe.
The present examine by Kieling et al. (2024) analysed the worldwide prevalence and well being burden of psychological problems and SUDs amongst 2,516 million people aged 5–24 years utilizing information from the 2019 GBD examine. Knowledge sources included nationwide well being surveys, hospital data, and worldwide stories. Knowledge had been stratified by distinct age teams (5–9, 10–14, 15–19, and 20–24 years) and gender. Findings had been cross-validated with unbiased datasets to make sure reliability. The Explanation for Dying Ensemble Mannequin (CODEm) was performed to regulate for comorbidities. Well being burden was quantified utilizing Years Lived with Incapacity (YLDs).
Outcomes
In 2019, 11.63% of people aged 5-24 years (roughly 293 million) had a minimum of one psychological well being dysfunction, whereas 1.22% (roughly 31 million) had a SUD (see Desk 1 under). Nervousness problems had been essentially the most prevalent (3.35%; 84 million), and schizophrenia was the least frequent (0.08%; 2 million). Boys confirmed increased charges of neurodevelopmental problems reminiscent of autism and attention-deficit hyperactivity dysfunction (ADHD), whereas ladies had higher prevalence of hysteria, temper, and consuming problems.
Concerning well being burden, psychological well being problems accounted for 20.27% (31.14 million of 153.59 million) of YLDs in youngsters and youths aged 5-24 years, the very best amongst all well being circumstances. SUDs contributed to 4.30 million YLDs. YLDs elevated dramatically with age, with nearly 5-fold will increase within the variety of YLDs within the age 20-24 years, in comparison with the age 5-9 years. Essentially the most stark enhance was for depressive problems, the place the variety of YLDs rose 35-fold from 5-9 years to 20-24 years.
From a broader life course perspective throughout all ages, 24.85% (31.14 million of 125.29 million) of whole YLDs related to psychological problems happen within the age 5 to 24 years, highlighting their vital burden in comparison with different well being circumstances like cardiovascular ailments (5.30%) and diabetes (3.15%).
Desk 1. Prevalence of a minimum of one psychological well being dysfunction throughout age teams
Age group (years) | Prevalence (% [95% CI]) |
5 to 9 | 6.81% [5.60 to 8.03] |
10 to 14 | 12.42% [10.57 to 14.45] |
15 to 19 | 13.96% [12.37 to 15.78] |
20 to 24 | 13.63% [11.91 to 15.53] |
5 to 24 (all) | 11.63% (weighted imply) |

In 2019, roughly 293 million youngsters and adolescents aged 5-24 years skilled a minimum of one psychological well being dysfunction, with anxiousness problems being essentially the most prevalent.
Conclusions
This examine by Kieling and colleagues (2024) highlights the worldwide prevalence of psychological well being problems in youngsters and adolescents aged 5–24 years, with anxiousness problems and temper problems being the first contributors. Psychological well being problems account for 20.27% of non-fatal well being burdens from all GBD problems in people aged 5-24 years. Furthermore, over the life course, 24.85% of all well being burden attributable to psychological well being problems was present in individuals aged 5-24 years, reversing the standard patterns noticed in different well being circumstances reminiscent of cardiovascular ailments and diabetes.
These psychological well being circumstances have a profound affect on schooling, social participation, and financial alternatives, with the burden notably excessive in low- and middle-income nations (LMICs). As such, this examine emphasises the urgent want for an elevated concentrate on early screening and intervention efforts, age-specific useful resource allocation, and prioritising adolescent psychological well being as a world well being concern. Policymakers are urged to deal with these challenges by evidence-based interventions and sustainable psychological well being insurance policies.

Between the ages of 5-9 and 20-24 years, the prevalence of getting a minimum of one psychological well being dysfunction doubles, highlighting the significance of early intervention and prevention efforts throughout this developmental interval.
Strengths and limitations
Strengths
- The examine adopts an age-stratified evaluation, providing detailed insights into psychological well being dysfunction prevalence and well being burden throughout distinct age teams throughout childhood and adolescence. It additionally offers evidence-based suggestions, emphasizing the significance of age-specific information for useful resource allocation and focused interventions.
- The examine used the information from GBD, which is collected from throughout 204 nations and areas and contains a variety of knowledge sources, reminiscent of systematic critiques, authorities stories, and worldwide databases. This worldwide protection permits for cross-regional comparisons, supporting extra inclusive and culturally delicate well being insurance policies.
- The examine employs a comorbidity adjustment mechanism to deal with the overlap of a number of problems inside people, lowering bias and guaranteeing unbiased and correct estimates of every dysfunction’s burden throughout age, gender, and area.
Limitations
- Knowledge from LMICs are restricted in high quality, with over 170 million youngsters and youths dwelling in data-scarce areas. Moreover, high-risk teams reminiscent of LGBTQIA+ youth and Indigenous adolescents are underrepresented. Such regional variations in information assortment and reporting additional have an effect on cross-region comparability.
- Knowledge sources differ by age group, with parental stories used for youthful youngsters and self-reports for adolescents, inflicting inconsistencies in information interpretation. Exclusion of subclinical displays additionally doubtlessly underestimates the true burden of psychological well being points.
- The examine depends on 2019 cross-sectional information, limiting insights into longitudinal impacts of those psychological well being circumstances. Moreover, it doesn’t account for the affect of the COVID-19 pandemic, which had a widespread unfavorable affect on the psychological well being of kids and adolescents.
- Variations in diagnostic requirements, cultural perceptions, and reporting practices throughout areas might introduce observer bias, affecting the accuracy and comparability of prevalence estimates. Though the information had been adjusted to account for identified biases, there stays some uncertainty about their accuracy.

Whereas the usage of a world dataset permits for cross-regional comparisons, there may be restricted information from low- and middle-income nations, alongside underrepresentation from high-risk teams.
Implications for apply
This examine highlights the pressing want for early intervention and age-specific psychological well being methods at a world scale. Insurance policies should prioritise enough funding, stigma discount, and accessible healthcare for kids and adolescents, particularly in LMICs.
Throughout my internship at a psychiatric hospital in China, I noticed that folks usually sought skilled assist solely when their youngsters’s educational efficiency had declined, and after a essential incident, reminiscent of self-harm or suicide. Earlier indicators of psychological misery had been missed or not recognised. This lack of understanding might result in delayed intervention, which might additional negatively affect educational efficiency, emotional stability, interpersonal relationships, and private improvement, all of which I witnessed throughout my intervention.
Moreover, psychological well being stigma stays a significant barrier to well timed entry to skilled assist (Golberstein et al., 2008). Addressing psychological well being in childhood and adolescence requires not solely scientific interventions however cultural shifts—fostering consciousness, acceptance, and proactive assist techniques all through society. This necessitates elevated communication between completely different techniques, reminiscent of faculties and healthcare companies.
Throughout my internship, I seen that faculties usually lacked the diagnostic instruments and coaching essential to establish and deal with psychological well being points at an early stage, whereas healthcare techniques incessantly operated in isolation, with restricted communication and collaboration with faculties and households. This brought about many missed alternatives for early intervention.

With a purpose to enhance well timed entry to psychological well being assist, we have to enhance consciousness of the early indicators of psychological misery in youngsters and adolescents.
Assertion of pursuits
None.
Hyperlinks
Main paper
Kieling, C., Buchweitz, C., Caye, A., Silvani, J., Ameis, S. H., Brunoni, A. R., … & Szatmari, P. (2024). Worldwide prevalence and incapacity from psychological problems throughout childhood and adolescence: proof from the worldwide burden of illness examine. JAMA Psychiatry, 81(4), 347-356.
Different references
Bullon, A. A. (2022). International burden of illness from psychological problems stays excessive. The Psychological Elf.
Cumber, B. (2024). Prevention is the place it’s at for kids and younger individuals’s psychological well being. The Psychological Elf.
Golberstein, E., Eisenberg, D., & Gollust, S. E. (2008). Perceived stigma and psychological well being care looking for. Psychiatric Companies, 59(4), 392-399.
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, Ok. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV problems within the Nationwide Comorbidity Survey Replication. Archives of Basic Psychiatry, 62(6), 593-602.